The ERS research network SARCOIDOMICS brings together European centers to improve understanding of sarcoidosis and the risk factors for a more severe disease course. The project promotes coordinated collection of clinical data, imaging findings, and biological samples, as well as connections between researchers from different countries.

The phase II RESOLVE-Lung trial evaluated namilumab in people with active pulmonary sarcoidosis. The trial included 107 participants. Namilumab did not provide a clinical benefit compared with placebo; a key outcome related to the need for additional treatment occurred in 37.5% of participants in the namilumab group and 23.5% in the placebo group.

WASOG, with support from AASOG, has published a position paper on a more thoughtful use of oral corticosteroids in sarcoidosis. These medicines can quickly reduce inflammation, but long-term use can cause significant side effects. The authors advocate assessing benefits and risks for each patient and considering steroid-sparing strategies when medically appropriate.

PREDMETH: in people with pulmonary sarcoidosis, methotrexate achieved a similar effect on lung function to prednisone after 24 weeks. The trial compared two initial treatment options, but this does not mean that either is suitable for everyone.